Sarmiza Stanca - A trimodal scanning probe sensor integrated into electrochemical photoinduced force microscopy. Application to cell membrane study
Montag, 26. Oktober, 16:00 Uhr, Fröbelstieg 1, HS 1
This work aims to build a trimodal scanning probe sensor (TrimodFM) integrated into an electrochemical photo-induced force microscopy setup (EC-PiFM) that synergistically record topographical, tip-electrochemi- cal and photoinduced force microscopical (PiFM) information at nanoscale in liquid. Two essential issues of the scanning force microscopy feedback instability in liquid and the water absorption of the infrared input signal in PiFM drive the methodological innovative solutions: 1) integration of a feedback stabilizer in liquid; 2) use a visible wavelength laser for PiFM; 3) operate PiFM at a tip resonance frequency adjusted via electrochemically locally grown porous platinum. The effort of implementing liquid cell in the system makes scientific sense when examinate dynamic processes at nanoscale, unapproachable straight in native form with other techniques. On this basis, we propose an EC-PiFM, by electronically connecting the tip-photoinduced records to the established simultaneous morphological-electrochemical records at nanoscale in liquid, which may solve central scientific issue of nanoscale study of the samples inaccessible with other methods. The sensor proofs its applicability to study at nanoscale the cell membrane, particularly ion channel inaccessible directly with other techniques.
