A trimodal atomic force mircoscope probe sensor for the physiological investigation of pores in native cell membranes

Dr. Sarmiza Stanca

A trimodal atomic force mircoscope probe sensor for the physiological investigation of pores in native cell membranes

The work aims to develop a trimodal atomic force microscopy (AFM) probe sensor, which synergistically combines the nanoscale topography recordings with nanoscale tip-electrochemistry recordings, to obtain nanoscale electro-structural information, and with photoinduced force microscopy (PiFM) recordings, to obtain vibrational modes of the molecules. The set-up conducted under the illumination of two lasers beams, complementarily combines tree sensitive techniques: I. Atomic force microscopy for morphological information at nanoscale, II. Photoinduced force microscopy for molecular vibrational information at nanoscale, and III. Tip electrochemistry for electrochemical information at nanoscale. This work benefits from photoinduced force microscopy, which offers great potential for investigating quantum phenomena at the nanoscale between tip and membrane.